Structure of NPC1-like intracellular cholesterol transporter 1 (NPC1L1) in complex with an ezetimibe analog
收藏Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Structure of NPC1-like intracellular cholesterol transporter 1 (NPC1L1) in complex with an ezetimibe analog Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(2S,3R)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-1-(4-{3-[(methylsulfonyl)amino]prop-1-yn-1-yl}phenyl)-4-oxoazetidin-2-yl]phenyl beta-D-glucopyranosiduronic acid, ... Authors: Huang, C.S, Yu, X, Min, X, Wang, Z. Deposit date: 2019-11-25 Release date: 2020-07-01 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Cryo-EM structures of NPC1L1 reveal mechanisms of cholesterol transport and ezetimibe inhibition Sci Adv, 6, 2020
创建时间：
2019-11-25
