Aβ peptides possess antimicrobial activity.
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https://figshare.com/articles/dataset/_A_946_peptides_possess_antimicrobial_activity_/530748
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资源简介：
The antimicrobial activity of synthetic Aβ1-42 (Aβ42), Aβ1-40 (Aβ40), LL-37 (LL-37), reverse Aβ42-1 (rAβ42), or scrambled Aβ42 (scAβ42) peptides were determined as minimal inhibitory concentrations (MIC) against 12 microorganisms. Antimicrobial activity was assayed by broth microdilution susceptibility test on 96-well plates with microbial growth in wells determined by visual inspection following an overnight incubation. Inhibition of growth in plate wells was confirmed by alamar blue cell viability assay and by surface plating of incubants on agar and counting CFU. Inoculums contained mid-logarithmic phase cells. Consistent with antimicrobial activity specific to the Aβ sequence, inhibition was not observed for reverse and scrambled peptides.
创建时间：
2010-03-03
