Pioglitazone induces extensive PPARg-dependent hepatic expression of nuclear-mitochondrial genes. Pioglitazone induces extensive PPARg-dependent hepatic expression of nuclear-mitochondrial genes

We report the results of RXR ChIP-Seq on 2 month old wildtype and liver specific PPARg knockout mice, fed control-diet or high fat-diet supplemented with Pio or vehicle for 12 weeks Overall design: Examination of the effect of Pioglitazone and high fat diet on liver RXR-DNA binding patterns