Men who have sex with men (MSM) account for more than half of all new HIV infections in the United States. However, the host-virus interaction in rectal mucosa during early rectal transmission of HIV-
In contrast to pathogenic HIV and SIV infection of humans and macaques, SIV infection of sooty mangabeys (SMs) is typically non-pathogenic despite high virus replication. A key feature of primary SIV
We profiled and characterized mRNA expression in colon of 12 chronically SIV-infected rhesus macaques (RMs) receiving vehicle (n=7) or delta-9-tetrahydrocannabinol (THC) and 4 uninfected control macaq
Shown are the most statistically significant patterns suggested by the gene expression data at peak VL (day 10) and post-peak (day 45+) in LN, blood and colon of SIV-infected animals.
Human bronchial epithelial cells (BEAS-2B cells) were treated with RSV at 1.0 MOI for 4 and 24 hours or control (vehicle-treated for 4 hours). Global gene expression was measured by Affy Hu133 plus 2.
