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A Genome-Wide CRISPR Screen Identifies BRD4 as a Regulator of Cardiomyocyte Differentiation [in-vivo scRNA-seq]

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NIAID Data Ecosystem2026-05-02 收录
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We employed single cell RNA sequencing to interrogate the consequence of conditional Brd4 deletion in the anterior heart field on heart development. Examination of single cell transcriptomes from cardiac progenitors captured at E9.5 from Brd4 floxed homozygous and Brd4 floxed het; Mef2c-AHF-cre hets. At least 2 biological replicate embryos were analyzed per genotype.

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2024-09-30
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