Additional file 6 of Superior breast cancer metastasis risk stratification using an epithelial-mesenchymal-amoeboid transition gene signature

Additional file 6: Table S5. A summary of the characteristics of the EMAT clusters obtained using lymph node-negative breast cancer patients from the METABRIC study. In this table, P stands for positive and N for negative. EMAT1 has the least similarity to hESC and is enriched in normal-like PAM50 subtype of breast cancer and has a good prognosis. EMAT2, the cluster with a relatively good prognosis, has little similarity to hESC, is enriched in Luminal A subtype and in ER-positive and PR-positive samples. EMAT3, the cluster with a relatively moderate prognosis, has a high degree of similarity to hESC, is enriched in Luminal B subtype and in ER-positive, PR-positive and HER2-negative samples. EMAT4, the cluster with the worst prognosis, shows the highest degree of similarity to hESC, is enriched in the basal-like subtype of breast cancer as well as ER-negative, PR-negative and HER2-negative samples.