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Identification of GDC-1971 (RLY-1971), a SHP2 inhibitor designed for the treatment of solid tumors

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Protein Data Bank Japan2023-10-25 更新2026-04-19 收录
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Identification of GDC-1971 (RLY-1971), a SHP2 inhibitor designed for the treatment of solid tumors Descriptor: (1S)-1-{6-[(1S)-1-amino-1,3-dihydrospiro[indene-2,4'-piperidin]-1'-yl]-3-(3,4-dihydro-1,5-naphthyridin-1(2H)-yl)-1H-pyrazolo[3,4-b]pyrazin-5-yl}ethan-1-ol, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 11 Authors: Tang, Y, Nugyen, V, Wilbur, J.D. Deposit date: 2023-06-15 Release date: 2023-10-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors. J.Med.Chem., 66, 2023
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2023-06-15
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