Differential gene expression in the stellate ganglia of 16 week wistar and spontaneously hypertensive rat samples

Hypertension remains a poorly understood condition, and the understanding of the sympathetic nervous systems role in this disease remains even more limited. In this study, RNA-sequencing is used to identify transcriptomal differences in the sympathetic stellate ganglia between the 16-week-old normotensive wistar strain and the spontaneously hypertensive rat strain.This dataset should allow for further molecular characterisation of hypertensive changes in a cardiac-innervating sympathetic ganglion.高血压仍是一种机制尚未完全阐明的疾病，而学界对交感神经系统在该疾病中所发挥的作用的认知则更为有限。本研究采用RNA测序（RNA-sequencing）技术，对16周龄正常血压Wistar大鼠品系与自发性高血压大鼠品系的星状交感神经节内的转录组差异进行了鉴定。本数据集可为解析支配心脏的交感神经节内高血压相关病变的分子特征提供研究基础。