P301S Mutant Tau-Driven Zebrafish Platform Enables Systematic Identification of Pharmacological GSK3B Inhibitors with Anti-Neurodegenerative Efficacy

Single-cell transcriptome sequencing provides high-resolution transcriptome data on the molecular mechanisms by which Tau P301S mediates Alzheimer's disease-like pathological changes in zebrafish, providing unique insights into the pathogenesis of Tau pathology-mediated cell-to-cell interactions in AD.