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Percent binding of BKPyV VP1 serotype Ib1 to HEK293TT cells in the presence or absence of antibodies. Median fluorescent intensity of plots shown in Fig 3 were extracted using FlowJo 10.7.1 and normalized to 100% VP1 binding (VP1-Ib1 binding to HEK293TT cells in the absence of antibodies) and 0% VP1 binding (HEK293TT cells with detection antibody only). For mAb 319C07 and mAb P8D11 a concentration-dependent decrease in VP1 binding to the cells was observed. mAb 24C03 does not inhibit VP1 binding to HEK293TT cells. n = 1, 15000 cells analyzed per concentration.

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Percent binding of BKPyV VP1 serotype Ib1 to HEK293TT cells in the presence or absence of antibodies. Median fluorescent intensity of plots shown in Fig 3 were extracted using FlowJo 10.7.1 and normalized to 100% VP1 binding (VP1-Ib1 binding to HEK293TT cells in the absence of antibodies) and 0% VP1 binding (HEK293TT cells with detection antibody only). For mAb 319C07 and mAb P8D11 a concentration-dependent decrease in VP1 binding to the cells was observed. mAb 24C03 does not inhibit VP1 binding to HEK293TT cells. n = 1, 15000 cells analyzed per concentration.

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2025-07-18
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