Bulk RNAseq of control and 5TGM1 myeloma-bearing bone marrow T, NK, and non-hematopoietic stromal cells from C57Bl/6 mice

We hypothesized that the immune microenvironment of the bone marrow influences the progression of myeloma outgrowth in the 5TGM1 transfer model of multiple myeloma. Therefore we sorted bone marrow T, NK, and non-hematopoietic stromal cells from control and tumor-bearing C57Bl/6 mice.我们提出假说：骨髓免疫微环境可影响多发性骨髓瘤5TGM1移植模型中骨髓瘤增殖的进程。据此，我们从对照组与荷瘤C57BL/6小鼠体内分选骨髓T细胞、自然杀伤（Natural Killer, NK）细胞及非造血基质细胞。