Asymmetric Total Synthesis of Griseofamine B and Its Three Stereoisomers
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https://figshare.com/articles/dataset/Asymmetric_Total_Synthesis_of_Griseofamine_B_and_Its_Three_Stereoisomers/19303762
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资源简介：
The first total synthesis of griseofamine
B is described starting
from l-4-bromo tryptophan methyl ester hydrochloride via
five steps and in 18% overall yield. Its three stereoisomers were
also synthesized following the same procedure with the yields of 5%,
19%, and 5%, respectively. In vitro antibacterial
activities were also evaluated. All four compounds exhibited less
potent activity than griseofamine A.
创建时间：
2022-03-03
