Multicomponent Synthesis of Functionalized Tetrahydroacridinones: Insights into a Mechanistic Route
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https://figshare.com/articles/dataset/Multicomponent_Synthesis_of_Functionalized_Tetrahydroacridinones_Insights_into_a_Mechanistic_Route/2112412
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资源简介：
A mechanistic
study of three-component reactions of various aromatic
amines with a number of aldehydes and 1,3-diones was achieved. The
unprecedented reaction involved a nucleophilic attack of an aromatic
amine on the in situ generated Michael adduct intermediate followed
by six-electron ring cyclizations. It is contrary to the common belief
that advocates involvement of coupling reactions between a Knoevenagel
adduct and an aromatic amine to deliver substituted tetrahydroacridinones.
创建时间：
2016-02-12
