Modeling Human Cortical Development in vitro using induced Pluripotent Stem Cells

ChEBI2012-10-19 更新2026-07-21 收录

神经细胞分化

皮层发育模型

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-41565 数据链接链接失效反馈

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Modeling Human Cortical Development in vitro using induced Pluripotent Stem Cells

创建时间：

2012-10-19

Supplementary Figure 1

细胞培养

神经细胞分化

It comprises of raw data and analysis file of Supplementary Figure 1 obtained by determining the effect of L929 conditioned medium on PC12 cell differentiation. PC12 cells were treated with naive medi

DataCite Commons2023-03-28 更新30

CHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis

神经细胞分化

CHD8基因功能

To understand the function of CHD8 in human ESC and neural differentiation, we generated the CHD8 knockout human ESCs and characterize the effect of loss-of-function of CHD8 on pluripotency maintenanc

NIAID Data Ecosystem10

Selected genes targeted by siRNAs during differentiation of Neuro2a cells.

神经细胞分化

RNA干扰

Genes were each targeted by 3 independent siRNAs as indicated. The features of average neurite length and neurite count were determined and are shown here. p-values in comparison to non-targeting cont

Figshare2015-12-02 更新00

Transcriptomes of mouse wildtype and Hoxa2-/- pharyngeal arches 1 and 2 at E9.0, E9.5, E10.0, and E10.5.. Transcriptomes of mouse wildtype and Hoxa2-/- pharyngeal arches 1 and 2 at E9.0, E9.5, E10.0, and E10.5.

神经细胞分化

咽弓模式形成

The Hox genes play a key role in specifying the axial identity of neural crest cells (NCCs) migrating into the pharyngeal arches of the developing mouse embryo. In the absence of Hoxa2, NCC derivative

NIAID Data Ecosystem20

Radial glial cells with mutated GemC1 NGAS data (RNA-seq data)

神经细胞分化

脑积水发病机制

Here we show that GemC1-deficiency in mice results in the development of severe hydrocephalus impaired cytoarchitecture and function of the SVZ neurogenic niche due to lack of mature ependymal cells.

NIAID Data Ecosystem10

Modeling Human Cortical Development in vitro using induced Pluripotent Stem Cells

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