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RNA-seq of GAP43 overexpressed and control SW620 cancer cells

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NIAID Data Ecosystem2026-03-12 收录
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We found GAP43 was significantly downregulated in colorectal cancer. So we reintroduced GAP43 to colorectal cancer cell line, and investigated the influence to cancer cells. In order to get the transcriptome-wide impact of GAP43 overexpression in colorectal cancer, we made stable transfected GAP43 in SW620 cancer cells, and mRNA-seq were performed (Sequenced with PE150, and 20M reads were generated.) This study provides the DEGs of GAP43 overexpressed and control colorectal cancer cells. Overall design: Changes in mRNA expression caused by GAP43 overexpression in colorectal cancer cell lines were examined.

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2021-01-16
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