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Effect of 4hr cortistatin A treatment on gene expression in SET2 cells.. Homo sapiens

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NIAID Data Ecosystem2026-03-07 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA273296
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资源简介:
We characterized the marine natural product cortistatin A (CA) as an inhibitor of CDK8 to determine whether pharmacologic inhibition of CDK8 regulates super-enhancer function and inhibits AML proliferation. In this series, we examine the transcriptional effect on SET2 cells of 4hrs exposure to CA to identify immediate effects. Overall design: SET2 cells were treated in triplicate with either DMSO or CA for 4hrs after which RNA was harvested and prepared for RNA sequencing to assess transcriptional changes.
创建时间:
2015-01-20
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