Crystal structure of the allosteric-defective chaperonin GroEL E434K mutant Descriptor: 60 KDA CHAPERONIN Authors: Cabo-Bilbao, A, Mechaly, A.E, Agirre, J, Spinelli, S, Sot, B, Muga, A, Guerin, D.M.A.

Protein Data Bank Japan2023-12-20 更新80

Phosphorylation of Hsp90 on serine residues in the charged linker modulates binding to interacting proteins and has implications for overall Hsp90β conformation

蛋白质磷酸化

分子伴侣作用机制

Serine residues in the charged linker region of human Hsp90beta are highly phoshporylated in vivo. Mutation of these residues to alanines resulted in altered binding of many Hsp90beta interactors. Thi

NIAID Data Ecosystem50

HEAT SHOCK PROTEIN 70 SUBSTRATE BINDING DOMAIN

蛋白质结构解析

热休克蛋白功能调控

HEAT SHOCK PROTEIN 70 SUBSTRATE BINDING DOMAIN Descriptor: GLYCEROL, Heat shock 70 kDa protein 1A/1B Authors: Kirby, C, Stams, T, Baird, J. Deposit date: 2014-11-04 Release date: 2015-01-14 Last modif

Protein Data Bank Japan2023-09-27 更新40

Subunit interactions influence the biochemical and biological properties of Hsp104

热休克蛋白功能调控

蛋白质复合物动力学

Point mutations in either of the two nucleotide-binding domains (NBD) of Hsp104 (NBD1 and NBD2) eliminate its thermotolerance function in vivo. In vitro, NBD1 mutations virtually eliminate ATP hydroly

PubMed Central2001-01-23 更新70

Crystal structure of the DnaK C-terminus (Dnak-SBD-C)

蛋白质晶体学

分子伴侣作用机制

Crystal structure of the DnaK C-terminus (Dnak-SBD-C) Descriptor: CALCIUM ION, Chaperone protein DnaK, PHOSPHATE ION, ... Authors: Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. Deposit

Protein Data Bank Japan2024-02-28 更新40

Two-step mechanism of J-domain action in driving Hsp70 function

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