Study of the (re)myelination in mouse model of multiple sclerosis treated with transceanial low-intensity focused ultrasound (FUS) neurostim

Multiple sclerosis (MS) is one of the most common causes of neurological disability in young adults in the Western world. In this disorder, the patient's immune system attacks the myelin sheath or the axons, causing inflammation and leading to irreversible neurological disability. Unfortunately, there are currently no widely used regenerative therapies in MS. In this context, the introduction of a non-invasive treatment promoting remyelination in MS patients has the potential to reduce long-term disability. In this framework, we plan to explore the efficacy of transcranial low-intensity focused ultrasound (FUS) neurostimulation treatment by comparing treated samples with healthy and diseased ones. Our study intends to provide a deeper understanding of myelin degeneration in MS and the impact of FUS treatment.