We sorted approx. 10000 neurons per sample from day one adult worms. We collected two wildtype samples and three thoc-5(wy822) mutant samples. Overall design: RNAseq of FACS-sorted C.elegans neurons f
WT or a strain lacking all six TAs were grown in M9-Glucose until late log phase and then challenged for 2 hours with ampicillin (100 μg/mL), ciprofloxacin (0.2 μg/mL), hydrogen peroxide (1.25 mM), or
This study reports two unrelated patients with a combined immunodeficiency. Whole-exome sequencing of both patients, their healthy parents and siblings identified a single de novo missense variant in
aWhen calculating the Km for isocitrate, the concentration of D-isocitrate was calculated as 50% of the total DL-isocitrate in this study. “na” indicates no measurable activity. Comparison of the kine
