True and estimated haplotype frequencies and correlation measures used by different methods.

Data was simulated under Scenario 7 (DominantDominant) with and . The table shows the mean of the relevant quantity (haplotype frequency or correlation measure) as estimated within cases or controls from 1000 simulation replicates. Wu: Estimated using EM algorithm as used by Wu et al. [1] methods. FE: Estimated based on counts in Table 2, as used by fast-epistasis methods. WZ: estimated using genotype-based correlation coefficient, as used by Wellek and Zigler inspired methods.