Modeling sex differences using isogenic human neural progenitor cells. Modeling sex differences using isogenic human neural progenitor cells
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA606067
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资源简介：
We developed a cellular model to study sex differences in humans. Using somatic cells from a mosaic Kleinefelter patient, we generated isogenic human induced pluripotent stem cell lines with different sex chromosome complements – 47,XXY / 46,XX / 46,XY and 45,X0. 46, XX and 46, XY hiPSCs were differentiated to neural progenitor cells and compared. Overall design: RNA-seq of six cell lines was analyzed: XX1, XX2, XX3, XY1, XY2, XY3. XX samples were compared to XY samples
创建时间：
2020-02-11
