We recently observed in a “two-hit” murine HFpEF model (Angiotensin II (AngII) + High-Fat Diet (HFD) or MHS) that stopping AngII, normalizing the diet, and introducing voluntary exercise (VE) helped r
We performed single cell RNA sequencing (scRNA-seq) for 6,574 cells from the aortic valves of C57BL/6J (wild type), Ldlr-/-, and Apoe-/- mice. The extensive single cell profiles depicted hyperlipidemi
