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Metadata record for the manuscript: The Aurora kinase/β-catenin axis contributes to dexamethasone resistance in leukemia

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Figshare2021-01-19 更新2026-04-08 收录
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https://springernature.figshare.com/articles/dataset/Metadata_record_for_the_manuscript_The_Aurora_kinase_-catenin_axis_contributes_to_dexamethasone_resistance_in_leukemia/13475916/1
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<b>Summary</b> This metadata record provides details of the data supporting the claims of the related manuscript: “The Aurora kinase/β-catenin axis contributes to dexamethasone resistance in leukemia”. The related study used a glucocorticoid-induced gene signature to develop a deep learning model that can predict dexamethasone sensitivity. Type of data: gene expression data, uncropped western blot, upstream kinase scores, synergy data. Subject of data: cell lines and patients with acute lymphoblastic leukemia <b>Data access</b> The gene expression data are openly available in <i>ArrayExpress</i> at https://identifiers.org/arrayexpress:E-MTAB-9250. The following additional data files underlying Figures 2, 5 and 6, and Supplementary Figures 1 and 7 are openly available in <i>figshare </i>at https://doi.org/10.6084/m9.figshare.13414706: Uncropped_WB_Figure_2d_j.pdf, Uncropped_WB_Figure_5e_f.pdf, Synergy_data.xlsx, Upstream Kinase Score_PTK_Figure_2a.png, Upstream Kinase Score_STK_Figure_2b.png, SUP-B15_EC50.pzf. A detailed spreadsheet of all data underlying the figures and supplementary files in the related manuscript is included with this metadata record in the file ‘Shah_Ahmed_Kazi_data_locations.xlsx’. This includes both data generated during the study and data from other sources used in the study. <b>Corresponding author(s) for this study</b> Julhash U. Kazi, Division of Translational Cancer Research, Department of Laboratory Medicine, Lund University, Medicon village Building 404:C3, Scheelevägen 8, 22363 Lund, Sweden. Email: kazi.uddin@med.lu.se. Phone: +46 46 222 6407.
提供机构:
Kinjal Shah; Julhash U. Kazi; Mehreen Ahmed
创建时间:
2021-01-19
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