Fuzzy logic rules define the osteogenic reaction in response to stimulatory inputs.

For the qualitative definition of each linguistic term, refer to Fig 10A. The symbol ⊕ indicates that the given conditions must occur simultaneously to produce the given intensity. The symbol ~ indicates that any choice of one or more from the chosen inputs produces the same intensity. The term ‘Not’, preceded by a linguistic level, indicates that the rule applied for all except the given level. The terms ‘ED’ and ‘LD’ stand for early differentiation and late differentiation, respectively. The rules are given in IF/THEN format in S2 Table in.