This project aims at deciphering the structural dynamics of G protein-coupled receptor (GPCRS) seven transmembrane domain (7TM) bound to a photoswitchable ligand and to decipher the structural basis o
Membrane proteins are prone to misfolding and degradation. This is particularly true for mammalian forms of the gonadotropin-releasing hormone receptor (GnRHR). Although they function at the plasma me
Using subtype-specific antisera, we were able to identify the recently described alpha subunits of G12 and G13 in platelet membranes as 43-kDa proteins. Activation of the thromboxane A2 and the thromb
