RNA sequencing profiling of placental tissues from placenta accreta and control pregnancies

Placenta accreta is a major cause of maternal morbidity and mortality in modern obstetrics. The study aims to identify the differently expressed lncRNA and mRNA in placenta accreta patients compared with controls and to determine biological pathways, which provides a novel insight ingto thepathogenesis of placneta accreta. Overall design: Total RNA from placental tissues obtained from 5 placenta accreta and 5 control patients at Caesarean section were extracted and performed RNA-seq.