STED:Supplement Information and Demo data
收藏Zenodo2026-02-01 更新2026-05-26 收录
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https://zenodo.org/doi/10.5281/zenodo.18450833
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STED: Single-cell Topic Modeling & Epigenetic Deconvolution
STED is a Python package designed for the analysis of single-cell and bulk multi-omics data. It leverages semi-supervised topic modeling (Anchored CorEx and LDA) to identify cell-type-specific gene modules in single-cell data and uses these models to deconvolve bulk RNA-seq, ATAC-seq and ChIP-seq data, estimating cell type proportions and predicting cell-type-specific epigenetic signals.
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2026-02-01



