Detection of evolutionary conserved and accelerated genomic regions related to adaptation to thermal niches in Anolis lizards

Understanding the genetic basis for adapting to thermal environments is important due to the serious effects of global warming on ectothermic species. Various genes associated with thermal adaptation in lizards have been identified mainly focusing on changes in gene expression or the detection of positively selected genes using coding regions. Only a few comprehensive genome-wide analyses have included noncoding regions. This study aimed to identify evolutionarily conserved and accelerated genomic regions using whole genomes of eight Anolis lizard species that have repeatedly adapted to similar thermal environments in multiple lineages. Evolutionarily conserved genomic regions were extracted as regions with overall sequence conservation (regions with fewer base substitutions) across all lineages compared with the neutral model. Genomic regions that underwent accelerated evolution in the lineage of interest were identified as those with more base substitutions in the target branch than i..., , , # Data from: Detection of evolutionary conserved and accelerated genomic regions related to adaptation to thermal niches in *Anolis* lizards

Contact: Fuku Sakamoto ([[e-mail]](mailto:[e-mail])), Masakado Kawata ([[e-mail]](mailto:[e-mail])).

## DESCRIPTIONS

The files contained under the \"Sakamoto_etal_2024_anole_pairwise_alignment\" directory are pairwise alignments of each *Anolis* species using the 13-chromosome genome of *Anolis carolinensis* as reference (compressed in gzip format). The alignments were generated by LastZ (Harris, 2007), subjected to the chaining and netting process introduced by Kent et al. (2003), and then filtered by a proprietary script. The naming convention is \"pairwise_[target species name]_carolinensis_[chromosome name of *A. carolinensis*].maf.\"

The files in the \"Sakamoto_etal_2024_anole_multiple_alignment\" directory are multiple alignments of *Anolis* species using the 13-chromosome genome of *Anolis ...