Crystal structure of Keap1 kelch domain in complex with a fluorenone-based small molecule inhibitor at 1.36A resolution
收藏Protein Data Bank Japan2024-11-27 更新2026-04-19 收录
下载链接：
https://pdbj.org/mine/summary/9f2p
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of Keap1 kelch domain in complex with a fluorenone-based small molecule inhibitor at 1.36A resolution Descriptor: (R)-2-(3-(((4-methoxyphenyl)sulfonamido)methyl)phenyl)-2-(9-oxo-9H-fluorene-4-carboxamido)acetate, DIMETHYL SULFOXIDE, Kelch-like ECH-associated protein 1, ... Authors: Narayanan, D, Bach, A, Gajhede, M. Deposit date: 2024-04-23 Release date: 2024-10-30 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (1.36 Å) Cite: Structure-Guided Conformational Restriction Leading to High-Affinity, Selective, and Cell-Active Tetrahydroisoquinoline-Based Noncovalent Keap1-Nrf2 Inhibitors. J.Med.Chem., 67, 2024
创建时间：
2024-04-23
