Comparison of different models on hold-out data.

Coherence score was calculated as exponential of the mean log-likelihood of each chromatin code in the hold-out test data, and was normalized by the best model coherence score (hence the 3rd order interaction model with regularization and fine tuning has normalized coherence score of 1). Numbers of non-zero parameters for self-energy, pairwise interaction and third-order interactions are shown in parenthesis, in that order.