RNA-seq analysis in NRG1 and enzalutamide treated 22Pc-EP cell line

Author summary from Gene Expression Omnibus: "Transcriptome prolifing analysis was performed in 22Pc-EP cells to identify differentially regulated genes by enzalutamide and NRG1. 22Pc-EP cells were treated with androgen receptor inhibition (enzalutamide) or a HER3 ligand NRG1 for 48hrs."<br/><br/>The data is from a study on tumor microenvironment-derived NRG1 promotes antiandrogen resistance in prostate cancer.

作者摘要摘自基因表达综合数据库：在22Pc-EP细胞中进行了转录组增殖分析，以识别由恩杂鲁胺和NRG1调控差异表达的基因。22Pc-EP细胞在48小时内分别接受雄性激素受体抑制剂（恩杂鲁胺）或HER3配体NRG1处理。数据来源于一项关于肿瘤微环境来源的NRG1促进前列腺癌抗雄激素耐药性的研究。