Enzymatic efficiencies determinations for selected subset of strains representative of each mutation type.

aCovalent FAD is expressed in pmol covalend FAD mg of protein−1 and is an estimation of the total amount of succinate dehydrogenase enzyme present in the mitochondrial preparation, presented values are the average of four individual determinations ± S.D.bMTT/PMS activity expressed as µmol PMS reduced MTT min−1 µmol covalent FAD−1. Values represent the means of at least 10 determinations ± S.D.cQo mediated DCPIP reduction expressed in µmol reduced DCPIP min−1 µmol covalent FAD−1 in the presence of 1 mM Qo. Values represent the means of at least 10 determinations ± S.D.