Stable Tricyclic Antitubercular Ozonides Derived from Artemisinin
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https://figshare.com/articles/dataset/Stable_Tricyclic_Antitubercular_Ozonides_Derived_from_Artemisinin/2120941
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资源简介：
New, highly stable tricyclic antitubercular
ozonides 9 and 10 derived from artemisinin
are reported in 39
and 9% yields, respectively. The ozonide groups of 9 and 10 were found to be stable under strong basic and acidic conditions.
The absolute configuration of ozonides 9 was confirmed
by X-ray crystallography. Ozonide 10 shows promising
antitubercular activity against M. tuberculosis H37Ra and M. tuberculosis H37Rv
with MIC values of 0.39 and 3.12 μg/mL, respectively.
创建时间：
2016-02-12
