The IC50 of these compounds are significantly different (p<0.05) from each other in different magnitude (nM vs µM); while compounds with the same magnitude (nM vs nM and µM vs µM) are not significantl
Results of LDH release (measured by the OD490 of assays on cell supernatants) from THP-1 cells in the presence of individual mNaps. Lysis buffer shows the LDH release from 100% of cells. (XLSX)
Cell morphology features, such as those from the Cell Painting assay, can be generated at relatively low costs and represent versatile biological descriptors of a system and thereby compound response.