Hazard ratios (and 95% CIs) for mortality according to the MR-pro-ADM, CT-pro-ET1 and copeptin levels.

The hazard ratios are displayed for a one-unit increase in the decadic log-transformed (corresponding to a ten-fold increase) of the plasma MR-pro-ADM, CT-pro-ET1 and copeptin concentration. Cardiovascular mortality was considered as sudden death (most probably circulatory or cardiac arrest) and death due to a cardiovascular event or disease (coronary artery disease, hypertensive crisis, stroke, peripheral artery disease).
Model 1: adjusted for demographics, hemodynamic and dialysis-specific risk factors.
- age.
- gender (male).
- time on dialysis.
- residual diuresis.
- shunt flow.
- vascular access on study enrolment (fistula, graft or catheter).
- systolic and diastolic blood pressure.
- interdialytic weight gain.
- pooled Kt/V.
Model 2: adjusted for all factors associated with mortality (significant difference between deceased and surviving patients).
- age.
- body mass index.
- duration of HD session.
- diastolic blood pressure.
- secondary hyperparathyroidism (represented by parathormone concentration).
- inflammatory status (represented by CRP concentration).
- comorbidities: systolic dysfunction (1 = yes), peripheral vascular disease (1 = yes), coronary artery disease (1 = yes), atrial fibrillation (1 = yes).