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HER2
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2025-11-02
相关数据集
ChIP-Seq of Transcriptional Components in Ly1 DLBCL and Colon carcinoma. Homo sapiens
Discovery of the genome-wide location of proteins using ChIP-Seq has allowed global mapping of the key transcription factors and chromatin regulators that control gene expression programs in various c
NIAID Data Ecosystem40
Epigenetic repression via DNA methylation and trimethylation of H3K27 alters gene expression in esophageal adenocarcinoma [RNA-Seq]
Epigenetic modifications in the form of altered DNA or histone methylation can influence gene expression patterns critical for neoplastic initiation and progression. The fact that abnormal gene expres
NIAID Data Ecosystem10
UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation [EPIC methylation]. UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation [EPIC methylation]
The E3 ubiquitin ligase UHRF1 is an established cofactor for replication-coupled DNA methylation inheritance. The current model posits a stepwise pathway in which UHRF1 engages nucleosomes through his
NIAID Data Ecosystem00
Genome-wide mapping of histone modifications and transcription factor occupancy in Fbw7 mutant cells [CUTandRUN]. Genome-wide mapping of histone modifications and transcription factor occupancy in Fbw7 mutant cells [CUTandRUN]
Fbw7 is one of the most highly mutated tumor suppressor genes in human cancers. Several Fbw7 mutation types have been found in cancers (e.g. Fbw7Arg/+, other missense mutations and Fbw7-/-). Fbw7Arg/+
NIAID Data Ecosystem10
Additional file 3: of Systems-epigenomics inference of transcription factor activity implicates aryl-hydrocarbon-receptor inactivation as a key event in lung cancer development
Excel table containing the results of a GSEA on the target genes in LungNet. (XLS 242 kb)
Figshare2023-06-01 更新10
