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HIV Integrase core domain in complex with inhibitor 2-(5-(3-fluorophenyl)-2-(2-(thiophen-2-yl)ethynyl)-1- benzofuran-3-yl)ethanoic acid

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Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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https://pdbj.org/mine/summary/7l23
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HIV Integrase core domain in complex with inhibitor 2-(5-(3-fluorophenyl)-2-(2-(thiophen-2-yl)ethynyl)-1- benzofuran-3-yl)ethanoic acid Descriptor: 3-{[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}benzoic acid, IODIDE ION, Integrase, ... Authors: Gorman, M.A, Parker, M.W. Deposit date: 2020-12-16 Release date: 2021-12-22 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Rapid development of potent inhibitors of the HIV integrase-LEDGF interaction by fragment-linking using off-rate screening To Be Published
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2020-12-16
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