Hepatic inactivation of murine Surf4 results in marked reduction in plasma cholesterol
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https://www.ncbi.nlm.nih.gov/sra/SRP400078
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资源简介:
SURF4 is a cargo receptor that has been implicated in the intracellular trafficking of PCSK9 and APOB - proteins involved in cholesterol transport and metabolism. We generated hepatic SURF4-deficient mice (Surf4(fl/fl) Alb-Cre+) to investigate the physiologic role of SURF4 in vivo Overall design: Anlysis of gene expression profile in livers of Surf4(fl/fl) Alb-Cre+ and Surf4(fl/fl) Alb-Cre- mice (n=3 per group) by RNA-seq
创建时间:
2022-10-29



