Protective effects of immunization with C-1 peptidases SmCB1 and FhCL1 alone and in combination with SG3PDH/PRX-MAP on male and female worm burdens and parasitological parameters.

Mice (10–12/group) were immunized with SmCB1 or FhCL1 combined with rSG3PDH/PRX-MAP and challenged 2 (panels 1–3) or 3 (panels 4 and 5) weeks after the last immunization.*Percent reduction was evaluated by the formula: % reduction = mean number in infected controls−mean number in infected, immunized mice/mean number in infected controls×100.aP values as calculated by Student 2-tailed t-test. NS = not significant.