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Crystal structure of HCV NS5B polymerase in complex with COMPOUND 2

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Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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Crystal structure of HCV NS5B polymerase in complex with COMPOUND 2 Descriptor: 2-{[(trans-4-methylcyclohexyl)carbonyl](propan-2-yl)amino}-5-[2-(trifluoromethyl)phenoxy]benzoic acid, Genome polyprotein, MAGNESIUM ION Authors: Coulombe, R. Deposit date: 2013-03-08 Release date: 2013-06-12 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure-based design of novel HCV NS5B thumb pocket 2 allosteric inhibitors with submicromolar gt1 replicon potency: Discovery of a quinazolinone chemotype. Bioorg.Med.Chem.Lett., 23, 2013
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2013-03-08
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