Data and code for Age-associated methylation at PFDA EWAS loci in clear cell renal cell carcinoma: a cross-cohort and cross-platform study

This record contains the machine-readable supplementary source data, derived score-level inputs, analysis scripts, environment manifests, provenance records, and lightweight verification workflow accompanying the manuscript “Age-associated methylation at PFDA EWAS loci in clear cell renal cell carcinoma: a cross-cohort and cross-platform study.”The package supports offline verification of the submitted statistics, fixed six-CpG meta-analysis, tumor-context analyses, and statistical sensitivity analyses. Large public methylation matrices, raw IDAT files, and controlled-access data are not redistributed; these materials require separate retrieval under the terms of their original repositories.The archived fixed six-CpG score used in the external analyses contains cg10948831/PBX1. The cg12121765/DLC1 locus was selected only in a distinct adaptive re-derivation using extreme-age-only or training-fold standardization and is not part of the archived fixed score.Version 1.0.0. The package is intended to support transparent review, reproducibility assessment, and reuse of the reported derived results.