five

Crystal structure of the ACVR1 (ALK2) kinase in complex with LDN-212854

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Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Crystal structure of the ACVR1 (ALK2) kinase in complex with LDN-212854 Descriptor: 1,2-ETHANEDIOL, 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline, Activin receptor type-1, ... Authors: Williams, E.P, Sorrell, F.J, Kopec, J, Nowak, R.P, Kupinska, K, von Delft, F, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N, Structural Genomics Consortium (SGC) Deposit date: 2017-09-06 Release date: 2017-09-20 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Structural basis for the potent and selective binding of LDN-212854 to the BMP receptor kinase ALK2. Bone, 109, 2018
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2017-09-06
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