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Hepatoselectivity of Statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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Hepatoselectivity of Statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors Descriptor: (3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-4-(morpholin-4-ylsulfonyl)-3-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase Authors: Finzel, B.C, Pavlovsky, A, Park, W.K.C. Deposit date: 2007-11-26 Release date: 2008-01-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.225 Å) Cite: Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
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2007-11-26
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