Basic Introductory Statistics for Radiation Oncologists

As part of the “Biostatistics and Evidence Appraisal for Radiation Oncologists”, an online seminar series is sponsored by the University of Cincinnati Department of Radiation Oncology and ROECSG (Radiation Oncology Education Collaborative Study Group https://voices.uchicago.edu/roecsg/), Dr. Clifton fuller presented exemplar data from the following publications of prospective trial performed under the auspices of the University of Texas MD Anderson Cancer Center (Trial No, 88-001):-Peters LJ, Goepfert H, Ang KK, Byers RM, Maor MH, Guillamondegui O, Morrison WH, Weber RS, Garden AS, Frankenthaler RA, et al. Evaluation of the dose for postoperative radiation therapy of head and neck cancer: first report of a prospective randomized trial. Int J Radiat Oncol Biol Phys. 1993 Apr 30;26(1):3-11. doi: 10.1016/0360-3016(93)90167-t. PMID: 8482629.-Rosenthal DI, Mohamed ASR, Garden AS, Morrison WH, El-Naggar AK, Kamal M, Weber RS, Fuller CD, Peters LJ. Final Report of a Prospective Randomized Trial to Evaluate the Dose-Response Relationship for Postoperative Radiation Therapy and Pathologic Risk Groups in Patients With Head and Neck Cancer. Int J Radiat Oncol Biol Phys. 2017 Aug 1;98(5):1002-1011. doi: 10.1016/j.ijrobp.2017.02.218. Epub 2017 Jul 10. PMID: 28721881; PMCID: PMC5518636.Data from these publications was anonymized (I.e. stripped of 45 CFR § 164.514- defined PHI identifiers); age values were “scrambled” in random order, such that they are not associated directly with the index patient case-data. The resultant dataset is presented as a .csv file for use for training and statistical instruction purposes.

作为“生物统计学与证据评估针对放射治疗医师”系列网络研讨会的一部分，辛辛那提大学放射治疗系与ROECSG（放射治疗教育协作研究组 https://voices.uchicago.edu/roecsg/）联合举办，Clifton Fuller 博士在以下由德克萨斯大学MD安德森癌症中心（试验编号，88-001）资助的前瞻性临床试验的出版物中展示了示例数据：

- Peters LJ, Goepfert H, Ang KK, Byers RM, Maor MH, Guillamondegui O, Morrison WH, Weber RS, Garden AS, Frankenthaler RA, 等人. 颈部及头颈癌术后放射治疗的剂量评估：前瞻性随机试验的首篇报道. 国际放射肿瘤学、生物学与物理杂志. 1993年4月30日;26(1):3-11. doi: 10.1016/0360-3016(93)90167-t. PMID: 8482629.

- Rosenthal DI, Mohamed ASR, Garden AS, Morrison WH, El-Naggar AK, Kamal M, Weber RS, Fuller CD, Peters LJ. 颈部及头颈癌患者术后放射治疗剂量-反应关系及病理风险组前瞻性随机试验的最终报告. 国际放射肿瘤学、生物学与物理杂志. 2017年8月1日;98(5):1002-1011. doi: 10.1016/j.ijrobp.2017.02.218. Epub 2017年7月10日. PMID: 28721881; PMCID: PMC5518636.

上述出版物中的数据经过匿名化处理（即去除了45 CFR § 164.514定义的PHI标识符）；年龄值以随机顺序“打乱”，以确保其与索引病例数据不直接关联。该数据集以.csv文件格式呈现，供训练和统计教学使用。