Molecular landscape of osimertinib resistance in patients and patient-derived preclinical models
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https://www.ncbi.nlm.nih.gov/sra/SRP353689
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资源简介:
In this study, we investigated the acquired resistance mechanisms in NSCLC patients and patient-derived preclinical models. We explored the genetic profiles of osimertinib-resistant NSCLC patient samples using targeted deep sequencing. In vitro and in vivo models harboring osimertinib resistance revealed potential novel treatment strategies after osimertinib failure.
创建时间:
2022-03-01



