Data from: Loss-of-heterozygosity facilitates a fitness valley crossing in experimentally evolved multicellular yeast
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https://datadryad.org/dataset/doi:10.5061/dryad.6q573n60m
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These data sets are generated to investigate a simple evolutionary
landscape that arises from underdominance at a single locus where the
fitness valley consists of only one less-fit genotype. We make use of an
experimental system previous evolved in the laboratory, the Saccharomyces
cerevisiae snowflake system. This system was experimentally selected
resulting in a significant evolutionary shift, the transition from
uni-to-multicellularity in asexual diploid populations. We carried out the
phenotypic and fitness characterization of the strains. Additionally, we
observed a rapid loss of heterozygosity (LOH) events in the heterozygote
strains. Experimental evolution starting with the heterozygote strains
suggests that LOH is common both under selection and without
selection. LOH event drive adaptation that may enable
rapid evolution in diploid yeast.
提供机构:
Dryad
创建时间:
2022-05-27



