RRP1B is a Metastasis Modifier that Regulates the Transcriptome through mRNA Splicing

ChEBI2014-06-08 更新2026-07-21 收录

癌症转移机制

RNA剪接调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-38669 数据链接链接失效反馈

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RRP1B is a Metastasis Modifier that Regulates the Transcriptome through mRNA Splicing

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2014-06-08

SRSF2 mutations impair hematopoiesis and alter exon recognition

髓系增生异常综合征

RNA剪接调控

Mutations within genes encoding spliceosomal proteins are the most common class of mutations in patients with myelodysplastic syndromes, yet it is currently not well understood how these mutations imp

NIAID Data Ecosystem70

shRNAi profiling of human MDA-MB-231 cells expressing anti-p53 (shp53) short-hairpin RNAs treated with TFGbeta or control

癌症转移机制

转录组功能分析

TGFβ ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers. The molecular nature of this switch remains enigmatic.

NIAID Data Ecosystem30

Chromodomain Helicase/ATPase DNA-Binding Protein 1-Like Gene (CHD1L) Expression and Implications for Invasion and Metastasis of Breast Cancer

癌症转移机制

肿瘤治疗靶点

BackgroundChromodomain helicase/ATPase DNA-binding protein 1-like gene (CHD1L), also known as ALC1 (amplified in liver cancer 1 gene), is a new oncogene amplified in many solid tumors. Whether this ge

Figshare2016-01-15 更新00

Study of transcriptional changes in MCM7-depleted and G1/S-arrested A549 and A375 cells

癌症转移机制

转录组学分析

We tested if the changes in cell invasion and migration observed after MCM7 depletion manifested in an altered gene expression profile. For this purpose, we performed RNAseq analysis after MCM7 knock-

NIAID Data Ecosystem40

Serial single-cell RNA sequencing unveils drug resistance and metastatic traits in stage IV breast cancer. Serial single-cell RNA sequencing unveils drug resistance and metastatic traits in stage IV breast cancer

癌细胞异质性

癌症转移机制

Background: Drug resistance and metastasis are complex processes that remain poorly understood on the molecular level with single-cell resolution. We profiled the transcriptomic changes at the single-

NIAID Data Ecosystem00

RRP1B is a Metastasis Modifier that Regulates the Transcriptome through mRNA Splicing

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