Integrated Immune Cell Atlas

This dataset represents the integrated immune cell atlas analyzed in the scHDeepInsight study. It contains over 460,000 immune cells collected from publicly available datasets generated using multiple sequencing platforms, including various versions of the 10x Genomics platform and Smart-seq. Batch effects across datasets were corrected using STACAS, resulting in a harmonized reference comprising 15 major immune cell types and 50 annotated subtypes. This reference provides a standardized framework for immune cell annotation and downstream analyses across heterogeneous single-cell datasets.

本数据集为scHDeepInsight研究中所分析的整合免疫细胞图谱。该数据集包含超过46万个免疫细胞，这些细胞采集自多个测序平台生成的公开可用数据集，涵盖10x Genomics平台的多款版本以及Smart-seq技术。研究通过STACAS对各数据集间的批次效应进行校正，最终得到一套标准化整合参考图谱，包含15种主要免疫细胞类型与50个已注释亚型。该参考图谱可为异质性单细胞数据集的免疫细胞注释及后续分析提供标准化框架。