Blood (∼20µl) was collected from female Npc1+/− (n = 2, age 63 and 66 days) and Npc1−/− mice (n = 2, age 63 and 66 days) by cheek bleed. Blood cell parameters were analyzed by Hemavet 950. Values repr
Additional file 6: Table S2. The single-guide RNAs (sgRNAs) to generate KO mice. The sequences of sgRNAs targeting mouse Zswim2, Rnf133, Rnf148, and Rnf151.