RNA-sequencing of PC3M prostate cancer cells depleted of the RNA binding protein HNRNPA2B1

RNA binding proteins (RBPs) play important roles in cellular stress responses. Here we investigated the association between HNRNPA2B1, an RBP upregulated in prostate cancer, and expression of genes in stress response pathways. HNRNPA2B1 depletion in vitro using siRNA resulted in altered expression of multiple genes in the unfolded protein response (UPR) pathway in PC3M prostate cancer cells. Overall design: 6 total samples, 3 replicates per condition